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Concussion studies in the news

Category : Information , Research , Safety

Study validates concussion assessment tools for children (published 7/26/17): http://www.aappublications.org/news/2017/07/26/Concussion072617

  • Woodinville Pediatrics uses the updated version of these tools, SCAT5 and Child SCAT5

General advice regarding concussion from the AAP: https://www.healthychildren.org/English/health-issues/injuries-emergencies/sports-injuries/Pages/Concussions.aspx

Study of football players’ brains, including a majority of ex-NFL players (published 7/25/17):

  • NY Times article about this study:  https://www.nytimes.com/interactive/2017/07/25/sports/football/nfl-cte.html 
    • “It is no longer debatable whether or not there is a problem in football — there is a problem,” Dr. McKee said.
  • Source article: http://jamanetwork.com/journals/jama/fullarticle/2645104
    • Relevant comments from the study: “There is substantial evidence that CTE is a progressive, neurodegenerative disease. In this study, 107 participants (96%) had a progressive clinical course based on informant report. In addition, pathological severity of CTE was correlated with age at death (Table 3). However, a postmortem study evaluates brain pathology at only 1 time point and is by definition cross-sectional. In addition, the participants were not observed longitudinally during life. Although associations with age in cross-sectional samples can result from age-related progression within individuals, they can also arise from birth cohort effects, differential survival, or age-related differences in how individuals were selected into the study. Population-based prospective studies are needed to address the issue of progression of CTE pathology and age at symptom onset.The strengths of this study are that this is the largest CTE case series ever described to our knowledge, more than doubling the size of the 2013 report,6 and that all participants were exposed to a relatively similar type of repetitive head trauma while playing the same sport. In addition, the comprehensive neuropathological evaluation and retrospective clinical data collection were independently performed while blinded to the findings of the other investigators.This study had several limitations. First, a major limitation is ascertainment bias associated with participation in this brain donation program. Although the criteria for participation were based on exposure to repetitive head trauma rather than on clinical signs of brain trauma, public awareness of a possible link between repetitive head trauma and CTE may have motivated players and their families with symptoms and signs of brain injury to participate in this research. Therefore, caution must be used in interpreting the high frequency of CTE in this sample, and estimates of prevalence cannot be concluded or implied from this sample. Second, the VA-BU-CLF brain bank is not representative of the overall population of former players of American football; most players of American football have played only on youth or high school teams, but the majority of the brain bank donors in this study played at the college or professional level. Additionally, selection into brain banks is associated with dementia status, depression status, marital status, age, sex, race, and education.36 Third, this study lacked a comparison group that is representative of all individuals exposed to American football at the college or professional level, precluding estimation of the risk of participation in football and neuropathological outcomes.”

Association of Playing High School Football With Cognition and Mental Health Later in Life (published 7/3/2017)

http://jamanetwork.com/journals/jamaneurology/article-abstract/2635831

  • “For men who attended high school in the late 1950s, playing high school football did not appear to be a major risk factor for later-life cognitive impairment or depression”

Reassuring News About Football and Cognitive Decline? Not So Fast (published 7/3/2017)

http://jamanetwork.com/journals/jamaneurology/article-abstract/2635828

  • “Although the Wisconsin Longitudinal Study provides a rich data set, there is no information on concussion history per se. The study evaluates the overall effect on long-term outcomes of playing football vs not playing football, but it does not directly evaluate the association of football-related exposure to concussion or subconcussion injury…”

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Meet the Pediatricians-June 15, 2017

Category : Uncategorized

We will have a meet-the-pediatricians’ evening meeting on Thursday, June 15 at 6:00 PM with Dr. Nakahara and Dr. Anderson. 

These meetings are for those expecting a child, or potentially new patients to our practice. If you are interested, please call our office at (425) 483-5437 to register. Meeting will be limited to the first 10 families to sign up. Please note we must limit attendance to those who sign up. See more information about these meetings here.


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Meet the Pediatricians-May 9, 2017

Category : Uncategorized

We will have a meet-the-pediatricians’ evening meeting on Tuesday, May 9 at 6:00 PM with Dr. Sliman and Dr. Bilger.

These meetings are for those expecting a child, or potentially new patients to our practice. If you are interested, please call our office at (425) 483-5437 to register. Meeting will be limited to the first 10 families to sign up. Please note we must limit attendance to those who sign up. See more information about these meetings here.


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EpiPen and EpiPen Jr recall

Category : Uncategorized

FDA alerts consumers of nationwide voluntary recall of EpiPen and EpiPen Jr

For Immediate Release

March 31, 2017

Release

The U.S. Food and Drug Administration is alerting consumers to Meridian Medical Technologies’ voluntary recalldisclaimer icon of 13 lots of Mylan’s EpiPen and EpiPen Jr (epinephrine injection) Auto-Injector products used for emergency treatment of severe allergic reactions. This recall is due to the potential that these devices may contain a defective part that may result in the devices’ failure to activate. The recalled product was manufactured by Meridian Medical Technologies and distributed by Mylan Specialty.

While the number of reported failures is small, EpiPen products that potentially contain a defective part are being recalled because of the potential for life-threatening risk if a severe allergic reaction goes untreated. Consumers should keep and use their current EpiPens if needed until they get a replacement. Consumers should contact Mylan at 800-796-9526 or customer.service@mylan.com with any questions.

As stated on the product label, consumers should always seek emergency medical help right away after using their EpiPens, particularly if the device did not activate.

At this time, the 13 lots identified – distributed between Dec. 17, 2015, and July 1, 2016 – are the only EpiPen lots impacted by the U.S. recall. Consumers who have EpiPens from lots that are not included in this recall, do not need to replace their EpiPen prior to its expiration date.

Product/Dosage NDC Number Lot Number Expiration Date
EpiPen Jr Auto-Injector, 0.15 mg 49502-501-02 5GN767 April 2017
EpiPen Jr Auto-Injector, 0.15 mg 49502-501-02 5GN773 April 2017
EpiPen Auto-Injector, 0.3 mg 49502-500-02 5GM631 April 2017
EpiPen Auto-Injector, 0.3 mg 49502-500-02 5GM640 April 2017
EpiPen Jr Auto-Injector, 0.15 mg 49502-501-02 6GN215 September 2017
EpiPen Auto-Injector, 0.3 mg 49502-500-02 6GM082 September 2017
EpiPen Auto-Injector, 0.3 mg 49502-500-02 6GM072 September 2017
EpiPen Auto-Injector, 0.3 mg 49502-500-02 6GM081 September 2017
EpiPen Auto-Injector, 0.3 mg 49502-500-02 6GM088 October 2017
EpiPen Auto-Injector, 0.3 mg 49502-500-02 6GM199 October 2017
EpiPen Auto-Injector, 0.3 mg 49502-500-02 6GM091 October 2017
EpiPen Auto-Injector, 0.3 mg 49502-500-02 6GM198 October 2017
EpiPen Auto-Injector, 0.3 mg 49502-500-02 6GM087 October 2017

 

The FDA asks health care professionals and consumers to report any adverse reactions or device malfunctions to the FDA’s MedWatchprogram, by:

The FDA, an agency within the U.S. Department of Health and Human Services, protects the public health by assuring the safety, effectiveness, and security of human and veterinary drugs, vaccines and other biological products for human use, and medical devices. The agency also is responsible for the safety and security of our nation’s food supply, cosmetics, dietary supplements, products that give off electronic radiation, and for regulating tobacco products.


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Meet the Pediatricians: April 5, 2017

Category : Uncategorized

We will have a meet-the-pediatricians’ evening meeting on Wednesday, April 5 at 6:00 PM with Dr. Johnson and Dr. Kaneshiro.

These meetings are for those expecting a child, or potentially new patients to our practice. If you are interested, please call our office at (425) 483-5437 to register. Meeting will be limited to the first 10 families to sign up. Please note we must limit attendance to those who sign up. See more information about these meetings here.


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